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Posts Tagged ‘Candida auris’

Types of Fungal Diseases –CDC

Posted by feww on August 16, 2017

Hormones, medicines, and changes in the immune system encourage fungal growth and cause infection

About 1.5 million different species of fungi are found on Earth, with 300 of those known to cause infections and sicken people. Fungi live outdoors in soil and on plants and trees as well as on many indoor surfaces and on human skin.

 Aspergillosis

 Microscopy of Aspergillus Fumigatus
Caused by the fungus Aspergillus and usually occurs in people with lung diseases or weakened immune systems.

Candidiasis

 Photomicrograph of the fungus Candida albicans
Caused by the yeast Candida. Candidiasis can occur in the mouth and throat, vagina, or the bloodstream.

Types of Candidiasis

Global Emergence of Candida auris

Candida auris is an emerging fungus that presents a serious global health threat. Healthcare facilities in several countries have reported that C. auris has caused severe illness in hospitalized patients. C. auris is often resistant to multiple antifungal drugs.

C. neoformans infection

 A photomicrograph of Cryptococcus neoformans using a light India ink staining preparation.
Caused by Cryptococcus neoformans, which can infect the brain (meningitis) in people with HIV/AIDS.

Fungal eye infections

 Photomicrograph showing conidiophores and conidia of the fungus Fusarium verticillioides
Different types of fungi can cause eye infections. These are rare but can develop after an eye injury.

Mucormycosis

 Microscopy of Apophysomyces, one of the causative agents of mucormycosis.
A rare infection that mainly affects people with weakened immune systems.

Ringworm

 Photomicrograph of the dermatophyte Trichophyton mentagrophytes
A common fungal skin infection that often looks like a circular rash.

Blastomycosis

 Histopathology showing a yeast cell of Blastomyces dermatitidis
Caused by the fungus Blastomyces, which lives in moist soil in parts of the United States and Canada.

Coccidioidomycosis (Valley Fever)

 Arthroconidia of Coccidioides immitis
Caused by Coccidioides, a fungus that lives in the southwestern United States and parts of Mexico and Central and South America.

C. gattii infection

 A photomicrograph of Cryptococcus
Caused by the fungus Cryptococcus gattii, which lives in soil in tropical and sub-tropical areas, the United States Pacific Northwest, and British Columbia.

Histoplasmosis

 A photomicrograph of Histoplasma capsulatum isolated from a soil sample.
Caused by the fungus Histoplasma, which lives in the environment, often in association with large amounts of bird or bat droppings.

Pneumocystis pneumonia (PCP)

 Histopathology showing Pneumocystis cysts in the lung of a patient with AIDS
Pneumocystis pneumonia (PCP) is a serious infection caused by the fungus Pneumocystis jirovecii. Most people who get PCP have a medical condition that weakens their immune system, like HIV/AIDS, or take medicines that lower the body’s ability to fight germs and sickness. Image: Pneumocystis jirovecii in the lung of an HIV/AIDS patient.

Sporotrichosis

 Photomicrograph showing Sporothrix schenckii.
Caused by the fungus Sporothrix, which lives throughout the world in soil and on plants.

Other pathogenic fungi

 Photomicrograph of Exserohilum rostratum
Exserohilum and Cladosporium are two examples of environmental molds.

Source: CDC

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Drug-Resistant ‘Japanese Fungus’ Spreads to 200 Patients in 55 UK Hospitals

Posted by feww on August 15, 2017

Candida auris: An emerging fungus that presents a serious global health threat –CDC

Healthcare facilities in several countries including the UK, United States, Japan, Venezuela, Colombia, India, Pakistan, Oman, Kuwait, Israel, South Africa and Spain have reported that C. auris has caused severe illness in hospitalized patients.

  • Some strains of C. auris are resistant to all three major classes of antifungal drugs [including the first-line anti-fungal drug fluconazole.] This type of multidrug resistance has not been seen before in other species of Candida.
  • Also of concern, C. auris can persist on surfaces in healthcare environments and spread between patients in healthcare facilities. [CDC]

C. auris was first identified in Japan eight years ago. The first case in Britain was detected in 2013, and has since spread to at least 200 patients in 55 UK hospitals.

On July 14, 2017, the US case count was updated to 98 across nine states, with a total of 68 cases in New York, and 20 in New Jersey.

  • The superbug is linked with bloodstream, wound and ear infections (otitis). 
  • Several strains of C. auris appear to be rapidly evolving.

Public Health England (PHE)

“As at the beginning of July 2017, 20 separate NHS Trusts and independent hospitals in the United Kingdom had detected over 200 patients colonised or infected with Candida auris,” PHE said.

“Three hospitals have seen large nosocomial [within hospital] outbreaks that have proved difficult to control, despite intensive infection prevention and control measures, though two of these outbreaks have been declared over and one is seeing significantly fewer numbers of new acquisitions.

 “Over 35 other hospitals have had patients known to be colonised with Candida auris transferred to them.”
A “biosafety” unit at Porton Down, Britain’s infamous chemical weapons lab, has been testing fungicidal activity of a variety of disinfectants and antiseptics, UK media reported.
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FIRE-EARTH Alert: C. auris – Update 2

Posted by feww on November 15, 2016

CJ Members

FIRE-EARTH Alert: Candida auris – Drug Resistance

  • Details of the Alert are available from FIRE-EARTH PULSARS.

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